INFECTIONS
anaerobic & surgical
FROM disease TO TREATMENT \ INFECTIONS anaerobic & surgical
ANAEROBIC & SURGICAL INFECTIONS
Anaerobic infections in surgical patients arise partly due to structural or functional defects that disrupt normal mucosal barriers, cause localized vascular insufficiencies, or create obstructions. These conditions compromise tissue oxygen levels, promoting the growth of anaerobic bacteria.1
References:
1.
Charles E. Edmiston, Candace J. Krepel, Gary R Seabrook, William G. Jochimsen, Anaerobic Infections in the Surgical Patient: MicrobialEtiologyand Therapy, Clinical InfectiousDiseases, Volume 35, IssueSupplement_1, September2002, Pages S112–S118, https://doi.org/10.1086/341931
POST OPERATIVE INFECTIONS
Post-operative abdominal infections are post operative infectious processes developing with in the abdominal cavity that may be caused by either bacterial or fungal pathogens with in the first few weeks after surgery and may be related to the operation itself or the postoperative period.
In the post operative intra abdominal infections (IAI), the infection extends beyond the hollow viscus of origin into the peritoneal space and is associated with either abscess formation or peritonitis. It can be classified as:
- Postoperative intra-abdominal abscess
- Postoperative (posttraumatic, post interventional) secondary peritonitis
- Tertiary peritonitis
It is often a polymicrobial infection with facultative aerobic enteric bacteria (e.g., Escherichia coli, Klebsiella spp., Citrobacter spp., Enterococcus spp.) and obligate an aerobic bacteria (e.g., Bacteroides spp., Peptostreptococcus spp., Clostridium spp.). In addition, intra abdominal fungal infection with Candida spp. can also occur.1
References:
1.
Sartelli, M., Coccolini, F., Kluger, Y. et al. WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections. World J Emerg Surg 16, 49 (2021).
https://doi.org/10.1186/s13017-021-00387-8
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