FROM disease TO TREATMENT \ GYNEACOLOGY infertility

INFERTILITY

Infertility is defined as the inability to achieve a clinical pregnancy after 12 months of regular, unprotected sexual intercourse or due to an impairment of a person’s capacity to reproduce either as an individual or with a partner.
According to the World Health Organization (WHO), in 2022 approximately 17.5% of adults worldwide experienced infertility, with similar rates observed across different countries.
In recent decades, the average number of live births per woman has declined markedly in many parts of the world.
Today, nearly half of the global population lives in countries where the fertility rate is below 2.1 births per woman β€” the threshold needed to maintain a stable population.
Infertility may be caused by a number of different factors, in either the male or female reproductive systems, but in 15–30% of the cases it is unexplained.
In women, infertility is mainly caused by ovarian disorders, along with factors such as endometriosis, uterine fibroids, and age. Among ovulatory disorders, about 70% are attributed to Polycystic Ovary Syndrome (PCOS).1
References:
1. Petraglia F, FauserBC. Endocrinology-Female Reproductive Dysfunction, 2020.Booklet; Institute for Health Metrics and Evaluation (IHME). Global Burden of Disease 2021: Findingsfrom the GBD 2021 Study. Seattle, WA: IHME, 2024WHO. Infertility prevalence estimates, 1990–2021. Geneva: World Health Organization; 2023.Carson SA, et al. JAMA 2021; 326(1):65-76

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